Stefano De Renzis

@derenzis
active 6 years, 8 months ago

Base

Full Name

Stefano De Renzis

Current position

Group Leader

Affiliation

EMBL-Heidelberg

Location

Heidelberg, Germany

Research interests

Membrane dynamics during tissue morphogenesis and differentiation

Webpage

http://www.embl.de/research/units/dev_biology/de_renzis/index.html

Research activity

Research

Research in my laboratory is focused on understanding how machineries controlling intracellular trafficking are re-organized during cell and tissue morphogenesis and how this, in turn, impacts on specific cell and tissue behavior during embryonic development. We address these questions using the early Drosophila embryo as model system during cellularization and early gastrulation stages.

Using a combination of imaging, genetics and biochemical approaches we wish to identify the cell biological basis underlying the pathways controlling changes in membrane dynamics during morphogenesis. Our long-term goal is to analyse the differentiation of intracellular pathways in other cell types and tissues. We wish to elucidate how machineries controlling intracellular trafficking reorient during differentiation and how this in turn impacts on global changes in tissue morphology.

Representative publications

21988917,17456005 ,16459304

Research keywords

Morphogenesis, Membrane trafficking, Endocytosis, Notch

Advanced

Latitude and Longitude

49.3846836646524,8.71061680168157