1. Carlos Estella

    Check our new paper: The bHLH-PAS Transcription Factor Dysfusion Regulates Tarsal Joint Formation in Response to Notch Activity during Drosophila Leg Development.

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    Check our newest paper on Plos Genetics on the development of joints. We found that the bHLH transcription factor dysfusion is a target gene of Notch and controls two important morphogenetic events that direct tarsal joint development such as programed cell death and epithelial cell shape.   http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004621
  2. Carlos Estella

    Our first Paper as a Group

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    Check our newest paper on Plos Genetics on the development of joints. We found that the bHLH transcription factor dysfusion is a target gene of Notch and controls two important morphogenetic events that direct tarsal joint development such as programed cell death and epithelial cell shape. http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004621  
  3. Barbara Jennings

    Newish Publication: The Groucho Co-repressor Is Primarily Recruited to Local Target Sites in Active Chromatin to Attenuate Transcription.

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    Debunked the old spreading and silencing models for Groucho-mediated repression - and discovered a few other things along the way.  It was an excellent and hugely enjoyable 3-way collaboration with Aamna and Gene. Also, a good experience dealing with PLOS Genetics. Now to write an epic novel about the backstory to getting...
  4. Luis M. Escudero

    New article on morphogenesis and image analysis

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    Hi everybody! We have just published our work in wing morphogenesis development using Graph Theory analysis to characterize subtle differences in organization between very similar epithelial images. Here is the PLOSONE link in case that you want to have a look at it: http://www.plosone.org/article/metrics/info%3Adoi%2F10.1371%2Fjournal.pone.0079227 Best!!! Luisma    
  5. Gabor Juhasz

    Myc, UPR, antioxidants and autophagy

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    Dear JEDIs, Did you know that the transcription factor Myc is required for autophagy, and vice versa, unfolded protein response-mediated autophagy and antioxidants are necessary to support the overgrowth of cells expressing oncogenic Myc in Drosophila larval and imaginal tissues? As wild-type cells grow just fine without autophagy or antioxidants,...