1. Gabor Juhasz

    Myc, UPR, antioxidants and autophagy

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    Dear JEDIs, Did you know that the transcription factor Myc is required for autophagy, and vice versa, unfolded protein response-mediated autophagy and antioxidants are necessary to support the overgrowth of cells expressing oncogenic Myc in Drosophila larval and imaginal tissues? As wild-type cells grow just fine without autophagy or antioxidants,...
  2. Ruben Cauchi

    Volume exploring Fly models of Motor Neuron Disease

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    Dear JEDIs, A volume I have edited on Drosophila models of Motor Neuron Disease has just been published.  This book singles out the past and recent accomplishments of Drosophila in modelling degenerative motor neuron disease including amyotrophic lateral sclerosis (Lou Gehrig’s disease), hereditary spastic paraplegias, Charcot-Marie-Tooth disease, spinal and bulbar muscular atrophy (Kennedy’s disease) and spinal muscular atrophy. The...
  3. Barbara Jennings

    First publication out from Jennings lab

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    We've just published a paper characterising the interaction between Pleiohomeotic (Pho) and Spt5 to regulation gene expression in Drosophila. It ended up being a tough project, we had to conquer the 4th chromosome and it probably raises more questions than it answers, so big relief to get it published. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0070184