1. Gabor Juhasz

    Myc, UPR, antioxidants and autophagy

    Dear JEDIs, Did you know that the transcription factor Myc is required for autophagy, and vice versa, unfolded protein response-mediated autophagy and antioxidants are necessary to support the overgrowth of cells expressing oncogenic Myc in Drosophila larval and imaginal tissues? As wild-type cells grow just fine without autophagy or antioxidants,...