PhD position in the Schirmeier lab (Münster, Germany) on Metabolic interactions in the Drosophila nervous system

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The Institute for Neuro- and behavioral biology at the University of Münster invites applications for a
PhD student position
(Salary Scale 13 TV-L / 65%)
Metabolic interactions in the Drosophila nervous system
in the group of Dr. Stefanie Schirmeier at the Institute of Neuro- and Behavioral biology. The
position will start at the earliest possible date. The contract will be fixed-term for three years with a
possible extension. The lab aims to analyze the metabolic homeostasis of the central nervous system.
Disturbance of neural metabolism is a feature of many neurodegenerative diseases. Several open
questions are being addressed using the model system Drosophila melanogaster: How are metabolites
distributed throughout the brain? How is the amount of metabolites supplied to the neurons regulated?
How is the import of carbohydrates from circulation coupled to neuronal activity? The transport proteins
implicated in carbohydrate uptake into and metabolite distribution within the brain are analyzed. In
addition, fluorescent metabolite nanosensors are used to unravel how metabolite distribution within the
brain is regulated and adapted to neuronal activity. The Ph.D. project will comprise methods of molecular
cloning, state of the art Drosophila genomic engineering and microscopy techniques.
The prerequisite for this appointment is a M.Sc. or equivalent degree in Biology, Biochemistry or related
fields. Individuals with a strong background in cell biology, developmental biology or molecular biology
are encouraged to apply. Experience in Drosophila genetics would be helpful, but is not essential.
The University of Münster is an equal opportunity employer and is committed to increasing the proportion
of women academics. Consequently, we actively encourage applications by women. Female candidates
with equivalent qualifications and academic achievements will be preferentially considered within the
framework of the legal possibilities. Disabled candidates with equivalent qualifications will be
preferentially considered.
Application documents should include a motivation letter, a curriculum vitae and a grade transcript.
Additionally, the applicant is expected to arrange for two letters of recommendation to be sent to the
address below. The application deadline is July 31st, 2016. Applications should be sent electronically as
one single file in pdf format to
Dr. Stefanie Schirmeier, Institut für Neuro- und Verhaltensbiologie, Badestr. 9, 48149 Münster

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